Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer

Hospital General Universitario Elche

Status and phase: Unknown; Phase 3

Conditions: Peritoneal Contamination After Ileocolonic Anastomosis; Intra-abdominal Abscess; Wound Infection

Treatments: Procedure: Handsewn anastomosis; Procedure: Stapled anastomosis

Study type: Interventional

Funder types: Other

Identifiers

NCT01458353

HGUElche1

Details and patient eligibility

About

Despite performing colonic surgery with strict asepsia measures, minimizing the contact of the colon lumen with the peritoneum, some contamination is nearly impossible to avoid. In stapled anastomosis, the hole opened in the colon is minimum, just the necessary for introducing the parts of the mechanical devices. In handsewn anastomosis, the colonic lumen is more exposed to the peritoneum, despite the colonic occlusion with clamps meanwhile the suture is performed.

Hypothesis: After stapled anastomoses, the peritoneal contamination should be lower than after handsewn ones.

Enrollment: 80 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• diagnosis of right-sided colon cancer and plans to undergo an elective surgery with curative aims.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups

Handsewn ileocolonic anastomosis

Experimental group

Description:

Swabs obtained from patients undergoing handsewn ileocolonic anastomosis

Treatment:

Procedure: Handsewn anastomosis

Stapled ileocolonic anastomosis

Experimental group

Description:

Swabs obtained for culture in those patients undergoing stapled ileocolonic anastomosis

Treatment:

Procedure: Stapled anastomosis