Microbiology, Antimicrobial Resistance and Outcomes of Neonatal Sepsis in China

Fudan University

Status: Not yet enrolling

Conditions: Antimicrobial Resistance; Neonatal Sepsis

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05089760

MAROC-ChiNICU

Details and patient eligibility

About

Neonatal sepsis remains one of the most important cause of mortality and morbidities in China. This study will establish a prospective registral cohort of all infants with culture-proven neonatal sepsis in Chinese NICUs participating in the Chinese Neonatal Network (CHNN). The microbiology, antimicrobial resistance patterns and neonatal outcomes will be described in detail for this cohort.

Full description

All infants with culture-proven sepsis in NICUs of CHNN will be enrolled in the study. Detailed data on microbiology, resistance pattern, neonatal mortality and morbidities will be collected and described. Risk factors for multi-resistant bacteria infections and for sepsis-related mortality will be identified.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 1 hour to 1 month old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to CHNN NICUs from 2022.1.1 to 2023.12.31
• Diagnosed with culture-proven sepsis

Exclusion criteria

• None

Trial design

1,200 participants in 1 patient group

Infants with bacteria sepsis

Description:

Infants diagnosed with culture-proven sepsis

Treatment:

Other: No intervention