Microbiology in Obstructive BIliary Disease

Hospital Universitario Dr. Jose E. Gonzalez

Status: Enrolling

Conditions: Biliary Disease

Treatments: Diagnostic Test: ERCP biliary culture

Study type: Observational

Funder types: Other

Identifiers

NCT05464693

GA21-00003

Details and patient eligibility

About

Patients admitted to hospital due to obstructive biliary disease secondary to benign and malign etiologies, undergoing ERCP, will be selected. Bile sample will be taken in ERCP procedure with sterile technique. Its macroscopic appearance will be assessed and biliary culture will be performed.

Full description

The sample of biliary aspirate will be assessed as follows.

1. Its macroscopic appearance will be analyzed: yellow, black, or purulent.
2. Biliary culture will be performed; if bacterial growth is observed, its identification will be carried out by means of MALDI-TOF MS mass spectrometry and antibiotic susceptibility tests will be carried out, using the automated VITEK system.

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with diagnosis or suspicion of biliary obstruction of any cause
• Any gender
• Over 18 years of age

Exclusion criteria

• Patients referred and previously treated at another hospital/clinic
• Previous ERCP
• Pregnancy
• Patient refusal to enter the study

Trial design

70 participants in 1 patient group

Patients with obstructive biliary disease

Description:

Patients admitted to hospital due to obstructive biliary disease secondary to benign and malign etiologies, undergoing ERCP, will be selected. Bile sample will be taken in ERCP procedure with sterile technique. Its macroscopic appearance will be assessed and biliary culture will be performed.

Treatment:

Diagnostic Test: ERCP biliary culture