Microbiota and Carcinogenesis of Small-intestine Neuroendocrine Tumors (Microbio-siNET)

Civil Hospices of Lyon

Status: Enrolling

Conditions: Small-intestine Neuroendocrine Tumors

Treatments: Other: Blood and stool sampling

Study type: Observational

Funder types: Other

Identifiers

NCT06624865

2023-A02667-38 (Other Identifier)

69HCL23_1290

Details and patient eligibility

About

The aim of the study is to investigate the impact of the microenvironment on tumorigenesis of small intestinal neuroendocrine tumors often located in the terminal ileum, without identified driver mutations.

Enrollment: 75 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with one or more small-intestine neuroendocrine tumor with indication of surgery
• Patient with consent for the collection, storage and reuse of data associated with his/her disease
• Age ≥ 18 years at the time of inclusion
• Non-objection statement obtained for participation in the study

Exclusion criteria

• Patients with poorly differentiated neuroendocrine carcinoma or NET (neuroendocrine tumors) of non-intestinal origin or mixed tumors (MiNEN)
• Pregnant, parturient or breast-feeding women
• Minors
• Persons deprived of liberty by judicial or administrative decision
• Adults under legal protection (guardianship, curatorship)

Trial design

75 participants in 1 patient group

patient with indication for small-intestine neuroendocrine tumor surgery

Description:

The target population for this study is consecutive patients with small-intestine neuroendocrine tumor for whom surgery is indicated

Treatment:

Other: Blood and stool sampling