Microbiota Changes in Acute Myeloid Leukemia Patients Undergoing Intensive Chemotherapy

University of Minnesota (UMN)

Status: Completed

Conditions: Acute Myeloid Leukemia

Treatments: Diagnostic Test: Stool Sample; Diagnostic Test: Sample Collection Blood

Study type: Observational

Funder types: Other

Identifiers

NCT03728699

HM2018-23 (Other Identifier)

2018NTLS107

Details and patient eligibility

About

This is a prospective, observational study to collect stool and blood from acute myeloid leukemia patients undergoing intensive chemotherapy.

Enrollment: 54 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Adults (ages 18 - 99 years) undergoing inpatient intensive chemotherapy for newly diagnosed, refractory, or relapsed AML. Patients may or may not have been exposed to any type of therapy before.
• Any intensive chemotherapy regimen defined as a planned ~4 week inpatient stay. Chemotherapy may be delivered for any number of days and on any schedule. Patients may be discharged from the hospital sooner than 4 weeks if the treating physician choose so, but the expectation at the initiation of chemotherapy must be ~4 weeks of inpatient stay, as is typical.
• Able to provide written voluntary consent before performance of any study related procedure.