Microbiota Community of Irritable Bowel Syndrome in Episodes and Remission Phase

Shandong University

Status: Unknown

Conditions: Irritable Bowel Syndrome

Treatments: Other: collect faeces from participants

Study type: Observational

Funder types: Other

Identifiers

NCT02566629

2015SDU-QILU-G11

Details and patient eligibility

About

Analyze microbiota community of irritable bowel syndrome in episodes phase and remission phase.

Full description

The pathophysiology of IBS is incompletely understood, it may involve an altered intestinal microbiota. Since the microflora composition of IBS is various in different studies, The investigators plan to compare the intestinal microbiota of IBS patients in episodes phase and remission phase with healthy controls,trying to find the difference.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• the presence of Rome III criteria for IBS ;
• Patients scheduled for colonoscopy examination or having negative screening examinations
• Aged between 18 and 65 years old

Exclusion criteria

• Antibiotic, probiotic or laxative usage within 4 weeks.
• organic gastrointestinal diseases
• Severe systematic disease: diabetes mellitus, hepatic, renal or cardiac dysfunction, thyroid disease or tumor etc.
• pregnancy or lactation.
• previous major or complicated abdominal surgery.
• severe endometriosis and dementia

Trial design

30 participants in 3 patient groups

IBS patients in episodes phase

Description:

collect faeces from IBS patients in episodes remission phase

Treatment:

Other: collect faeces from participants

IBS patients in remission phase

Description:

collect faeces from IBS patients in remission phase

Treatment:

Other: collect faeces from participants

healthy controls

Description:

collect faeces from healthy controls

Treatment:

Other: collect faeces from participants