Microcirculation of the Thenar Eminence

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Elective Cardiac Surgery

Treatments: Other: microcirculatory reactivity

Study type: Observational

Funder types: Other

Identifiers

NCT01748266

1008018

2010-A00172-37 (Other Identifier)

Details and patient eligibility

About

Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) have been thought to be at the origin of organ dysfunction. Though, few studies correlated microvascular alterations with outcome. Investigators aimed at firstly describing microcirculation with near infra red spectroscopy (NIRS) and secondly correlating NIRS parameters with intensive care length of stay and organ dysfunction.

Full description

40 patients at high risk of post operative systemic inflammatory response syndrome after an elective cardiac surgery with CPB were included in this prospective observational study. Patients were studied during the first 48 postoperative hours. Microcirculation of the thenar eminence was analyzed by NIRS technology, through the StO2 and the resaturation slope after an ischemic challenge. Organ dysfunction was assessed with the SOFA score.

Enrollment: 40 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• scheduled for an elective cardiac surgery at high risk of post operative systemic inflammatory response syndrome

Exclusion criteria

• BMI>35

Trial design

40 participants in 1 patient group

microcirculatory reactivity

Description:

Patients were studied during the first 48 postoperative hours. Microcirculation of the thenar eminence was analyzed by NIRS technology, through the StO2 and the resaturation slope after an ischemic challenge.

Treatment:

Other: microcirculatory reactivity