Microcirculatory Assessment in Patients With Trauma and Severe Burns

University of South Alabama (USA)

Status: Withdrawn

Conditions: Trauma; Burns

Treatments: Other: micro-imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT01922960

12-092

Details and patient eligibility

About

Predict the development of multiple organ failure in patients with trauma and severe burns.

Full description

Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock).

The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with severe burns/trauma ages 19-80. Patients undergoing elective abdominal or cardiothoracic surgery ages 19-69 years old

Exclusion criteria

• Patients undergoing elective surgery < 19 years old.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

micro-imaging

Other group

Description:

Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints. Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 \& Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,\& closing of surgical wound.

Treatment:

Other: micro-imaging