Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome

Universidade Federal do Rio de Janeiro

Status: Completed

Conditions: Lipid Profile; Anthropometric Measure; Insulin Resistance; Oxidative Stress; Blood Pressure

Treatments: Dietary Supplement: microencapsulated fish oil; Dietary Supplement: microencapsulated conjugated linoleic acid; Dietary Supplement: light fruit jam

Study type: Interventional

Funder types: Other

Identifiers

NCT02183922

181/10

Details and patient eligibility

About

Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile in women with metabolic syndrome and genotype Pro12Pro in the PPAR gamma 2 gene.

Enrollment: 37 patients

Sex: Female

Ages: 30 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adults women (30-45 years old);
• diagnosis of metabolic syndrome, as defined by the International Diabetes Federation;
• Pro12Pro genotype in gene PPARγ2.

Exclusion criteria

Participants were excluded if they:

• Were allergic to strawberries or fish
• Were pregnant or lactating
• Took fatty acid supplements
• Had undergone bariatric surgery or were being treated nutritionally or pharmacologically for reducing BM, or had taken anti-obesity drugs during the previous three months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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37 participants in 3 patient groups, including a placebo group

light fruit jam

Placebo Comparator group

Description:

The placebo group received light fruit jam (15 g/day) during 12 weeks.

Treatment:

Dietary Supplement: light fruit jam

microencapsulated fish oil

Experimental group

Description:

The microencapsulated fish oil group received light fruit jam with microencapsulated fish oil (3 g/day) during 12 weeks.

Treatment:

Dietary Supplement: microencapsulated fish oil

microencapsulated conjugated linoleic acid

Experimental group

Description:

The microencapsulated conjugated linoleic acid group received light fruit jam with microencapsulated conjugated linoleic acid (3 g/day) during 12 weeks.

Treatment:

Dietary Supplement: microencapsulated conjugated linoleic acid