Microneedling Combined With Topical Crisaborole 2 % Ointment in Treatment of Vitiligo.

Tanta University

Status: Not yet enrolling

Conditions: Vitiligo

Treatments: Procedure: microneedling with topical crisaborole

Study type: Interventional

Funder types: Other

Identifiers

NCT07088276

36264MS976/6/25

Details and patient eligibility

About

The goal of this clinical trial is to learn if topical crisaborole ointment works to treat vitiligo. It will also learn about the safety of the drug. The main questions it aims to answer are:

Can the drug cause repigmentation of vitiligo lesions when used as topical form after microneedling? What medical problems do participants have when the drug used?

Participants will:

Visit the clinic once every 2 weeks to have the microneedling sessions for 3 months. and also they will have narrow band UVB sessions two times per week.

Record any side effect they have during or after the sessions.

Enrollment: 20 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients suffer from non-segmental stable vitiligo.
• Patients who will accept to be included in the study and will sign a written consent.

Exclusion criteria

• Patients with history of koebnerization or any sign of disease activity.
• Patients with keloid tendency.
• Patients with active infection.
• Pregnant or lactating woman.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

the main patch with microneedling and topical crisaborole and two patches as control

Other group

Description:

each patient will have 3 vitiligo patches one will be treated by microneedling and topical application of crisaborole and the other 2 patches will be considered as control patches

Treatment:

Procedure: microneedling with topical crisaborole