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Microneedling Versus Carboxytherapy in Stria Distensae Rubra

A

Alexandria University

Status

Active, not recruiting

Conditions

Striae Distensae

Treatments

Device: microneedling
Device: Carboxytherapy

Study type

Interventional

Funder types

Other

Identifiers

NCT07001644
0107162

Details and patient eligibility

About

The aim of this study is to evaluate and compare the efficacy and safety of microneedling and carboxytherapy either with or without platelet-rich plasma in the treatment of striae distensae rubra.

Enrollment

50 patients

Sex

Female

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Female patients.
  • Age ranging from 18-45 years old.
  • Fitzpatrick skin type III-IV.
  • Striae distensae rubra on the abdomen (bilateral and more or less symmetrical).

Exclusion criteria

  • Patients taking immunosuppressants or having any disease affecting wound healing including diabetes.
  • Patients receiving systemic glucocorticoids for chronic health conditions.
  • Patients with chronic dermatologic diseases such as psoriasis and vitiligo.
  • Pregnant and lactating females.
  • Patients with a tendency for keloid formation.
  • Patients with endocrine disturbance.
  • Patients with autoimmune diseases, systemic diseases such as severe anemia, respiratory, cardiac, renal or liver disorder.
  • Patients with bleeding and coagulation disorders.
  • Patients who received any form of treatment for their SD in the past 6 months.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

50 participants in 2 patient groups

treated with microneedling
Active Comparator group
Description:
microneedling with topical application of PRP on one side of abdomen and microneedling only on the other side
Treatment:
Device: microneedling
treated with carboxytherapy
Active Comparator group
Description:
carboxytherapy with intradermal injection of PRP on one side of abdomen and carboxytherapy only on the other side
Treatment:
Device: Carboxytherapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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