MicroRNA as Markers in Testicular Cancer

Haukeland University Hospital

Status: Enrolling

Conditions: Non-Seminoma Testicular Cancer; Stage I Testicular Cancer; Testicular Germ Cell Cancer; Stage IV Testicular Cancer; Relapse Testicular Cancer; Stage III Testicular Cancer; Stage II Testicular Cancer; Seminoma

Treatments: Other: Biomarker analysis

Study type: Observational

Funder types: Other

Identifiers

NCT04914026

2015/1475

Details and patient eligibility

About

The main objective of this study is establish the performance of miR371 in management of testicular cancer

Full description

The main objective of the study is to asses the sensitivity and specificity of microRNA-371a-5p (miR371) in detection of viable testicular germ tumour cells. To assess the utility of miR371 at orchiectomy, during treatment and surveillance and in early detection of recurrence.

Enrollment: 350 estimated patients

Sex: Male

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with suspected testicular cancer, referred to orchiectomy.
• Patients diagnosed with testicular germ cell cancer.
• Age 18-70 years of age.
• Must be able receive information and to consent.

Exclusion criteria

• Other prior or concomitant malignancy (other than testicular cancer).
• Other diseases or conditions that hinder the ability to receive information and to participate in follow-up procedures.