MicroRNA Expression Profile in Human Vitreous of Patients With Various Vitreoretinal Diseases Requiring Vitrectomy

Kyorin University

Status: Completed

Conditions: MicroRNA Expression Profile in Human Vitreous of Various Vitreoretinal Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT01674023

No.518

Details and patient eligibility

About

MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear. Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of patients with various vitreoretinal disorders and compare with that of patients with macular holes which are suggested to be similar to that of healthy subjects.

Enrollment: 8 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• any patients undergoing vitrectomy for various vitreoretinal diseases

Exclusion criteria

• previously vitrectomized eyes

Trial design

8 participants in 1 patient group

human vitreous, human blood serum, PCR

Description:

human vitreous and blood serum sampling, PCR 1ml of human vitreous and 3ml of human blood serum of patients with various vitreoretinal diseases