MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection

King Chulalongkorn Memorial Hospital

Status: Enrolling

Conditions: Gastric Cancer; MicroRNAs

Treatments: Diagnostic Test: MicroRNA

Study type: Observational

Funder types: Other

Identifiers

NCT05901376

RP023

Details and patient eligibility

About

The goal of this observational study is to compare specific microRNA levels from the plasma of gastric cancer patients and healthy volunteers to see if there is an upregulated expression in gastric cancer patients.

The main question it aims to answer is:

• Can microRNAs be effectively used as diagnostic biomarkers for gastric cancer?

Participants will be asked for their consent to obtain 5 cc of blood.

Enrollment: 280 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria for Gastric Cancer group:

• Recently diagnosed gastric cancer
• Never received any treatment for gastric cancer

Inclusion Criteria for Control group:

• Age 50 or above
• Underwent elective upper gastrointestinal endoscopy and negative for gastric cancer
• No prior history of gastric dysplasia or cancer

Exclusion Criteria:

• Patients who cannot give informed consent
• Pregnancy
• Lymphoma

Trial design

280 participants in 2 patient groups

Gastric Cancer

Treatment:

Diagnostic Test: MicroRNA

Control

Treatment:

Diagnostic Test: MicroRNA