Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a Chronic Total Occlusion (FLOW-CTO)

Parc de Salut Mar

Status: Unknown

Conditions: Coronary; Ischemic; Coronary Microvascular Dysfunction; Chronic Total Occlusion of Coronary Artery; Microvascular Coronary Artery Disease

Treatments: Diagnostic Test: Invasive coronary physiology

Study type: Observational

Funder types: Other

Identifiers

NCT05197361

FLOW1

Details and patient eligibility

About

It is an observational study which objective is to analyze, through a series of invasive parameters, the state of the coronary microvasculature immediately after the successful percutaneous coronary intervention of a chronic total occlusion and at 6 months after the index procedure.

The aim of the study is to check the variation in the values of the index of microcirculatory resistance (IMR) and invasive absolute coronary flow (AF). The working hypothesis is that, in the follow-up of these patients, AF will increase significantly with respect to its baseline and, conversely, IMR will be reduced during the follow-up.

Enrollment: 34 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Those patients with a clinical indication for percutaneous coronary intervention of a chronic total occlusion. As a routine clinical practice in our center, it is proposed to perform a angiographic follow-up 6 months after the index procedure.

Exclusion criteria

• No specific exclusion criteria.

Trial design

34 participants in 1 patient group

Global cohort

Description:

Invasive coronary physiology parameters estimation, including: FFR, CFR, IMR, Absolute coronary flow (AF). AF derived resistances

Treatment:

Diagnostic Test: Invasive coronary physiology