Microvascular Effects of Intravenous Esmolol During Postoperative Atrial Fibrillation (FANI)

Civil Hospices of Lyon

Status: Completed

Conditions: Postoperative Atrial Fibrillation

Study type: Observational

Funder types: Other

Identifiers

NCT03646773

69HCL16_0743_1

Details and patient eligibility

About

Background: Postoperative atrial fibrillation (POAF) is commonplace after cardiothoracic surgery. A rate control strategy by using short-acting beta blockers is recommended as a first-line therapy in patients without hemodynamic instability. Microcirculatory effects of POAF and esmolol have not been yet investigated. The investigators made the hypothesis that POAF without hemodynamic instability would induce microvascular dysfunction which could be reversed by intravenous esmolol.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• conventional cardiac surgery
• thoracic surgery

Exclusion criteria

• Postoperative atrial fibrillation leading to hemodynamic instability