Microvascular Reactivity.

Yale University

Status: Completed

Conditions: Retinopathy; Diabetes; Vascular Pathology

Treatments: Device: Laser Doppler Flowmetry with topical acetylcholine and nitroglycerin

Study type: Observational

Funder types: Other

Identifiers

NCT00259701

HIC-12397-1

Details and patient eligibility

About

This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).

Full description

Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: diabetic. -

Exclusion Criteria: not on nitrates or mydriatic eye drops within 48 hours.