Microvascular Reactivity in Prepubertal Children (MicroChild)

Rio de Janeiro State University

Status

Completed

Conditions

Child, Only

Endothelial Dysfunction

Obesity

Treatments

Diagnostic Test: inflammatory biomarkers

Diagnostic Test: nailfold videocapillaroscopy

Study type

Observational

Funder types

Other

Identifiers

NCT03171441

2218-CEP/HUPE

Details and patient eligibility

About

This is a cross-sectional study aimed to investigate microvascular reactivity in prepubertal children according to adiposity status.

Full description

The investigators aimed to investigate microvascular reactivity in prepubertal and to compare these data in different groups according to adiposity status. Firstly, The investigators recruited only children from 5 to 10 years at prepubertal status. After excluding those with exclusion criteria and the acceptance (from their parents) to participate in the study, a blood sample was collected and an appointment at BioVasc lab was programmed. At this day, participants were subject to nail fold videocapillaroscopy. A method used to investigate microvascular reactivity by a non-invasive mean. After this, participants children were followed to the outpatient's care unit to continue follow-up.

Enrollment

98 patients

Sex

All

Ages

5 to 10 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

children aged from 5 to 10 years at prepubertal Tanner´s status

Exclusion criteria

puberty
regular use of any medication
hypertension
heart disease
renal and blood diseases .the presence of any acute or chronic inflammatory/infectious diseases. .presence of diabetes mellitus.