Microvesicle Production After Acute Trauma and Its Clinical Impact on Venothromboembolism

Mayo Clinic

Status: Completed

Conditions: Venothromboembolism

Study type: Observational

Funder types: Other

Identifiers

NCT01264458

10-001889

Details and patient eligibility

About

The purpose of this research study is to look at how trauma affects the ability of blood to clot. The blood of people who suffer a traumatic injury can under-clot or over-clot, and this research study will look at blood drawn from people after they suffer a traumatic injury to see how well their blood clots.

Enrollment: 1,234 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female patients 18 years of age or older
• Blunt trauma patients including those with closed head injury
• Penetrating trauma patients

Exclusion criteria

• Are on therapeutic anticoagulation
• Have preexisting coagulopathy
• Patients greater than 12 hours from time of injury
• Have history of malignancy or preexisting diagnosis of sepsis or renal failure
• Patients with burn injuries
• Male and female patients younger than 18 years of age
• Pregnant patients

Trial design

1,234 participants in 2 patient groups

Traumatic Injury

Description:

Trauma patients arriving at Saint Mary's Emergency Department

Control group