Middle Age MuScle Krill Study (MASK)

University of Glasgow

Status: Enrolling

Conditions: Sarcopenia

Treatments: Dietary Supplement: Vegetable oil; Dietary Supplement: Krill oil

Study type: Interventional

Funder types: Other

Identifiers

NCT06005064

MASK

Details and patient eligibility

About

This study will determine the effect of 6 months of supplementation with krill oil on muscle strength and mass in middle-aged adults. The study hypothesis is that krill oil supplementation will increase muscle strength and mass in middle-aged adults.

Enrollment: 92 estimated patients

Sex: All

Ages: 35 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Be 35-60 years old
• Have a BMI of less than 35kg/m2

Exclusion criteria

• People with diabetes, severe cardiovascular disease, seizure disorders, uncontrolled hypertension (>150/90mmHg at baseline measurement), cancer or cancer that has been in remission <5 years, ambulatory impairments which would limit the ability to perform assessments of muscle function, dementia, on anticoagulant therapy, and/or taking medication known to affect muscle (e.g., steroids).
• People who have allergies to seafood, and/or regular consumption of more than 1 portion of oily fish per week.
• People who perform regular (>1 day/week) resistance exercise training.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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92 participants in 2 patient groups, including a placebo group

Intervention

Experimental group

Description:

Krill oil 4g/day for 24 weeks

Treatment:

Dietary Supplement: Krill oil

Placebo

Placebo Comparator group

Description:

Vegetable oil 4g/day for 24 weeks

Treatment:

Dietary Supplement: Vegetable oil