Midline Catheter and Its Impact on Central Lines Removal in ICU (MIDREA)

Centre Hospitalier Departemental Vendee

Status

Terminated

Conditions

Vascular Access Device

Treatments

Device: PVC

Device: Midline

Study type

Interventional

Funder types

Other

Identifiers

NCT03675711

CHD 037-18

Details and patient eligibility

About

The study will evaluate 2 strategies to remove central venous catheter (CVC): in one part, the insertion of a midline catheter and in the other part, the conventional insertion of peripheral venous catheter (PVC)

Full description

Patients will be randomised when the last indication for CVC has disappeared, which means parenteral nutrition or vasopressors administration.

They will be randomised either in the midline group or in the PVC group.

In the midline group, a midline catheter will try to be inserted before the 48th hour after last indication for CVC disappeared.
In the PVC group: a PVC will try to be inserted before the 48th hour after last indication for CVC disappeared.

If successful, CVC will then be removed. If not, a PVC will try to be inserted daily till success or worthlessness of a venous line or death.

The presence of a CVC will be assessed at the 96th hour after disappearance of last CVC indication.

Enrollment

83 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

≥18 years of age
admitted to ICU since at least 48h
with a perfusion CVC inserted
requiring or having required invasive mechanical ventilation
lack of formal indication to CVC maintenance (weaning of vasopressors and/or parenteral nutrition) since at least 24 hours
indication to maintain a venous access

Exclusion criteria

Lack of patient or next of kin consent
Personnel for insertion of midline catheter not available
Admission in ICU before study start
Admission following a transfer from another ICU
Patient with an implantable port or a peripherally inserted central catheter (PICC Line)
Known intolerance to components of study Midline device
Past history of irradiation of insert area of midline catheter
Past history of bilateral axillary lymph node dissection
Pre-existing skin infection on upper limb
Patient with a treatment-limitation decision
Patient admitted after cardiac arrest with non-shockable rhythm
Moribund
Pregnancy, breastfeeding woman
Patient under legal guardianship
Patient hospitalized without consent and/or deprived of liberty by court's decision