Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Status
Conditions
Treatments
Details and patient eligibility
About
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions. To our knowledge, there are no trials comparing mifepristone to laminaria in a standard clinical setting with standardized misoprostol induction protocol to examine the issue of induction to delivery time. We hypothesize that mifepristone will work at least as well as laminaria for midtrimester cervical ripening prior to induction of labor with misoprostol.
Sex
Ages
Volunteers
Inclusion criteria
- pregnant women with fetal anomalies, aneuploidy, or demise at 15-22 weeks gestation
- age greater than 16
- able to speak English
Exclusion criteria
- prior uterine scar or
- allergy or history of bad reaction to any of the study drugs or
- history of chronic adrenal failure or
- porphyria or
- concurrent long-term corticosteroid treatment
Trial design
Primary purpose
Allocation
Interventional model
Masking
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal