Milk Components and Metabolic Syndrome (MoMS)

University of Copenhagen

Status: Completed

Conditions: Obesity; Metabolic Syndrome

Treatments: Behavioral: Milk Components and Metabolic syndrome

Study type: Interventional

Funder types: Other

Identifiers

NCT00785499

MoMS D204

Details and patient eligibility

About

Milk contains a vast number of bioactive components that have been suggested to have a positive impact on human health, of special interest is the effects related to metabolic syndrome and obesity but the effect of the individual milk components is not clear. This study examine whether it is beneficial for overweight and obese children to increase the intake of skim milk, or whey or casein in relation to bodyweight and markers of MS.

The participants will be randomized to receive skim milk, whey milk drink, casein milk drink or mineral water for 3 mo. They will be examined at baseline, end of intervention and followed up 3 month later.

Enrollment: 193 patients

Sex: All

Ages: 12 to 15 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 12 years to 15 years old
• iso BMI larger than 25
• habitual milk intake less than 250 ml/day
• non-smoker
• healthy at the time of inclusion

Exclusion criteria

• chronic illnesses
• intake of antibiotic 1 mo before start of intervention

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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193 participants in 4 patient groups

skim milk

Experimental group

Description:

skim milk

Treatment:

Behavioral: Milk Components and Metabolic syndrome

whey

Experimental group

Description:

Whey milk drink

Treatment:

Behavioral: Milk Components and Metabolic syndrome

casein

Experimental group

Description:

casein milk drink

Treatment:

Behavioral: Milk Components and Metabolic syndrome

water

Active Comparator group

Description:

Danish mineral water

Treatment:

Behavioral: Milk Components and Metabolic syndrome