Milking Versus Delayed Cord Clamping in Full Term Neonates (MDCCT)

Ahmed Mohamed El Kotb Abdel Fattah

Status: Completed

Conditions: Neonatal Anemia

Treatments: Procedure: cord milking; Procedure: delayed cord clamping

Study type: Interventional

Funder types: Other

Identifiers

NCT02454101

delayed cord clamping in term

Details and patient eligibility

About

To compare the short term risks and benefits of cord milking 5 times toward the neonate with delayed cord clamping for 120 seconds in the full term neonate delivered by cesarean section.

Full description

Abstract Context: milking of the umbilical cord toward the neonate 5 times and delayed cord clamping both are good procedures to prevent anemia in neonates .

Objective: To investigate the effects of delayed umbilical cord clamping for 120 seconds, compared with milking of the cord 5 times toward the neonate on hemoglobin level after 6 weeks, Intubation,Respiratory distress,Clinical jaundice,Neonatal Intensive Care unit (NICU) admission,Apgar score (after 5 minutes of delivery).

-Maternal,Need for blood transfusion,Additional need for therapeutic uterotonics,Post postpartum hemorrhage (blood loss > 500cc),Intensive Care unit admission.

Design: Randomized controlled trial. Setting: Ain Shams university maternity hospital. Participants:300 full term infants born after a low risk pregnancy by cesarean section delivery.

Intervention: Infants were randomized to delayed umbilical cord clamping (≥120 seconds after delivery) or cord milking (5 times to ward the neonate).

Enrollment: 300 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant females going for cesarean section that completed 37 weeks of gestation
• Medically free

Exclusion criteria

• Known congenital anomalies of fetus.
• Rhesus sensitization.
• Fetal hydrops.
• Medical disorder (preeclampsia - diabetes mellitus - hypertension - SLE).
• Need for urgent resuscitation.
• Multiple pregnancies.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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300 participants in 2 patient groups

cord milking

Other group

Description:

milking of the umbilical cord 5 times toward the neonate

Treatment:

Procedure: delayed cord clamping

delayed cord clamping

Other group

Description:

delayed cord clamping for 120 seconds

Treatment:

Procedure: cord milking