Milrinone During Living Donor Hepatectomy

Seoul National University

Status: Completed

Conditions: Hepatectomy

Treatments: Drug: milrinone; Drug: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT00966745

mil_living_liver_donor

Details and patient eligibility

About

Maintaining a low central venous pressure during living donor hepatectomy is routine practice. The investigators tried to test the hypothesis that using milrinone to maintain a low central venous pressure (CVP) during is associated with a superior surgical field and less blood loss.

Enrollment: 38 patients

Sex: All

Ages: 19 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Living liver donors

Exclusion criteria

• Donors with concurrent cardiac, pulmonary, and urologic disease
• Hepatectomy performed laparoscopically

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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38 participants in 2 patient groups, including a placebo group

milrinone

Active Comparator group

Description:

milrinone infusion

Treatment:

Drug: milrinone

placebo

Placebo Comparator group

Treatment:

Drug: placebo