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Mindfulness and Cognition in Schizophrenia

C

Centre Hospitalier Universitaire de Saint Etienne

Status

Terminated

Conditions

Schizophrenia

Treatments

Behavioral: Mindfulness

Study type

Interventional

Funder types

Other

Identifiers

NCT03318640
2017-A02921-52 (Other Identifier)
1708181

Details and patient eligibility

About

Mindfulness (innovative and integrative practice in care) allows the individual to adapt his/her behavior (physical and emotional), in a stressful environment, by regulating cardiac activity, especially the parasympathetic system. In schizophrenia, despite the positive effect of treatments on symptoms (delusions and hallucinations), patients have altered markers of the parasympathetic (high frequency, HF) system. The investigator propose a session of Mindfulness Based Stress Reduction (MBSR) for patients suffering from schizophrenia in order to measure the impact on the parasympathetic system (HF), self-awareness (being well in one's body and being aware of their own actions; EASE) and cognition (attention) in relation to the management of conflicts or emotions. The study compare with patients who receive a session of techniques based on the management of emotions and social cognition (cinemotion, Michael's Game and Tom Remed).

Enrollment

34 patients

Sex

Male

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • DSM-IV diagnosis of schizophrenia (men only)
  • aged 18-55
  • with no change in antipsychotic medication and clinical status within four weeks prior to the study
  • affiliates or entitled to a social security scheme
  • who have given their informed consent before participating in the study.

Exclusion criteria

  • History of head trauma, neurological disease or not stabilized serious physical illness
  • Disorders related to the use of a psychoactive substance, as defined by the DSM-IV (abuse, dependence or withdrawal) within 6 months
  • Beta blocking and anti-arrhythmic medications.

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

34 participants in 2 patient groups

Mindfulness
Experimental group
Description:
Patient will have 8 sessions (1h30) of mindfulness based on Kabat-Zinn program during one month.
Treatment:
Behavioral: Mindfulness
Control
No Intervention group
Description:
Patient will have usual medical care.

Trial contacts and locations

1

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Central trial contact

Beatrice DEYGAS; Anne GROSSELIN

Data sourced from clinicaltrials.gov

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