Mindfulness and Yoga Therapy for Acute Pain in Sickle Cell Disease

The University of Texas System (UT)

Status: Completed

Conditions: Sickle Cell Crisis; Sickle Cell Disease

Treatments: Behavioral: Mindfulness meditation, breathing exercises (including incentive spirometry), and yoga therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05572294

STU-2021-0729

Details and patient eligibility

About

Patients with sickle cell disease suffer from acute and chronic pain that diminishes their quality of life. The purpose of this study is to assess the feasibility and acceptability of mindfulness meditation, breathing exercises, and gentle yoga therapy as supportive measures for the management of acute vaso-occlusive pain crises in the inpatient setting.

Full description

This is a prospective single arm study of mindfulness interventions for sickle cell patients admitted with an acute vaso-occlusive pain crisis. Patients will be accrued over a consecutive 12 week period. All genotypes of sickle cell disease will be eligible for enrollment.

After providing informed consent, the patients will have access to 4 videos on their hospital room television. The videos contain guided mindfulness meditation, breathing exercises (including the use of an incentive spirometer), and gentle yoga therapy that can be performed in the supine position from a hospital bed. Videos vary in length from 5-12 minutes. Participants will have the ability to watch the videos as many times as they choose. They may also turn off the video at any time.

The primary outcome is feasibility and acceptability of the intervention. We will record objective data on how many videos are watched by each participant, as well as the percentage of each video completed. We will obtain information about the participants' perception of the intervention through a post-intervention survey and interview.

Enrollment: 39 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with sickle cell disease, any genotype
• Adult patients at least 18 years of age
• English speaking
• Admitted to Clements University Hospital with an acute vaso-occlusive pain crisis

Exclusion criteria

• Unable to follow simple instructions
• Admitted to the intensive care unit

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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39 participants in 1 patient group

Mindfulness and Yoga Therapy

Experimental group

Description:

Participants will have access to video-guided mindfulness interventions.

Treatment:

Behavioral: Mindfulness meditation, breathing exercises (including incentive spirometry), and yoga therapy