Mindfulness Intervention for Maltreatment-Related Cognitive Decline

Kyungpook National University Chilgok Hospital

Status: Active, not recruiting

Conditions: Maltreament; Health Adult Subjects

Treatments: Behavioral: Mindfulness-Based Online Training Program

Study type: Interventional

Funder types: Other

Identifiers

NCT07066800

2025-05-020-001

Details and patient eligibility

About

The goal of this clinical trial is to examine whether an online mindfulness-based training program can help improve cognitive function including attention, emotional regulation, and mental health (such as depression and anxiety) in young adults (ages 19 to 40) who have experienced maltreatment. The main questions it aims to answer are:

• Can a 4-week online mindfulness program improve cognitive function including attention in adults with a history of maltreatment?
• Does the program reduce symptoms of depression and anxiety compared to a control group?

Researchers will compare a mindfulness training group with a waiting-list control group to see if the intervention leads to improvements in psychological and cognitive functioning.

Participants will:

• Complete psychological and cognitive assessments before and after the 4-week period
• Watch weekly online educational and mindfulness practice videos (e.g., breathing, body scan, walking meditation)
• Perform weekly mindfulness-based assignments through a study website
• Engage in optional interaction via a chat channel

Enrollment: 104 estimated patients

Sex: All

Ages: 19 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 19 to 40 years

• Individuals with a history of childhood maltreatment, defined as meeting at least one of the following on the Early Trauma Inventory-Short Form (ETISR-SF)

  • At least one subscale (general trauma, physical abuse, emotional abuse, sexual abuse) exceeding established cut-off scores (Plaza et al., 2011)
  • A Global score ≥ 4 on ETISR-SF

• No current or past history of major internal medical or psychiatric disorders

• Willing and able to provide written informed consent

• Able to access and use an online platform (computer or mobile device)

Exclusion criteria

• Intellectual disability, defined as IQ ≤ 70
• History of traumatic brain injury
• Ongoing or past (≥6 months) psychiatric treatment for a diagnosed mental disorder
• Presence of severe psychiatric symptoms impairing reality testing or basic daily functioning (Note: Individuals with mild to moderate depressive symptoms based on screening are not excluded)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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104 participants in 2 patient groups

Experimental Arm - Mindfulness Intervention Group

Experimental group

Description:

* Participants receive a 4-week online mindfulness-based training via a structured website (videos, weekly tasks). * Includes breathing, body scan, and walking meditation sessions

Treatment:

Behavioral: Mindfulness-Based Online Training Program

Control Arm - Waiting List Group

No Intervention group

Description:

* Participants do not receive the intervention during the initial 4 weeks. * Serve as a comparison group for pre-post outcomes. * May receive the intervention after the study period (if planned as ethical compensation).