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Mindreading in Adults With Autism Spectrum Disorder

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National Taiwan University

Status

Enrolling

Conditions

Autism Spectrum Disorder

Treatments

Other: no intervention

Study type

Observational

Funder types

Other

Identifiers

NCT04010409
201809069RINA

Details and patient eligibility

About

This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Full description

Autism spectrum disorder (ASD) is a clinical syndrome characterized by mindreading deficits, or Theory of Mind deficits. The Reading the Mind in the Eyes task (abbreviated as the Eyes task) was developed to assess the mindreading deficits as a hallmark of social deficits of ASD. This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. All the participants will complete clinical measures and the Eyes task. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Enrollment

60 estimated patients

Sex

All

Ages

20 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Adult aged between 20 and 50 years who had a diagnosis of ASD based on DSM-5.
  • Had a full-scale IQ > 70 on WAIS-IV.

Exclusion criteria

  • A history of major mental illness (e.g., bipolar affective disorder, schizophrenia) or neurological diseases.
  • Visual impairment and that would preclude participation.

Trial design

60 participants in 2 patient groups

ASD Group
Description:
Autism spectrum disorder participants, no intervention
Treatment:
Other: no intervention
TD Group
Description:
Typically developmental controls,no intervention
Treatment:
Other: no intervention

Trial contacts and locations

1

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Central trial contact

Yi Ling Chien, M.D., Ph.D.

Data sourced from clinicaltrials.gov

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