Mineral-Homeostasis in Continuous Renal Replacement Therapy

Heinrich-Heine University, Duesseldorf

Status: Completed

Conditions: Acute Renal Failure

Study type: Observational

Funder types: Other

Identifiers

NCT01946113

4209

Details and patient eligibility

About

Acute renal failure is a common complication in intensive care unit patients. In 10% of cases renal replacement therapy becomes necessary. Current devices have increase filter patency and efficacy. However, magnesium, calcium and phosphate are eliminated as well. However, the extend of this elimination hase not been quantified. Thus, we want to

1. record retrospectively how often abnormal values for phosphate, magnesium and calcium occurred during routine renal replacement therapy in 2011 and 2012.
2. prospectively evaluate the same parameters during routine treatment in 2013 and 2014

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• intensive care unit patients with acute renal failure undergoing continuous renal replacement therapy
• older than 18 years of age

Exclusion criteria

• age less than 18 years
• pregnancy
• contraindications against continuous renal replacement therapy

Trial design

200 participants in 2 patient groups

Retrospektive Cohort

Description:

Patients requiring renal replacement therapy from 2011 to 2012 on intensive care unit

Prospektive Cohort

Description:

Patients requiring renal replacement on intensive care unit in 2013 and 2014