Minimally Invasive Non Surgical Therapy Versus Conventional Scaling and Root Planing for Treatment of Periodontitis (MINST)

University of Ljubljana

Status: Completed

Conditions: Periodontal Diseases

Treatments: Procedure: MINST; Procedure: Conventional SRP

Study type: Interventional

Funder types: Other

Identifiers

NCT04036513

2019-1-1

Details and patient eligibility

About

Minimally invasive non-surgical therapy (MINST) is a new approach towards regeneration of deep periodontal defects. Important part of MINST procedure, besides usage of magnification loupes and piezo-electric devices seems to be the usage of special mini-curettes, originally mini-five and after mini-five of Hu-Friedy. So far only descriptive data about the clinical effects of such procedure are available and comparative studies that would include other treatment alternatives are lacking. Therefore, the aim of our study is, on split-mouth model, to compare the number of diseased sites (defined by probing depth ˃ 4 mm and bleeding on probing) after conventional non-surgical therapy and MINST with the usage of special mini-curettes. In addition, new 3D parameters obtained from 3D optical scanning will be developed for evaluation of volume changes of soft tissues.

Enrollment: 20 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• periodontitis Stage III, grade B/C
• at least 20 teeth
• at least 9 teeth (excluding molars) in the upper jaw
• without FPD, implants
• without occlusal trauma signs
• no pathology of endodontic origin
• without chronic systemic diseases
• no periodontal treatment in the last 6 months

Exclusion criteria

• poor oral hygiene (PI > 20% at evaluation)
• antibiotic treatment in the last 6 months or during the observation period
• pregnant women, lactation, serious chronic systemic diseases, medication with known influence on periodontium or wound healing

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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20 participants in 2 patient groups

MINST

Experimental group

Description:

Usage of magnification loupes, specific thin and delicate tips together with piezoelectric device and specifically designed Hu-Friedy "mini five", "micro mini five", and "after five" Gracey curettes under local anaesthesia.

Treatment:

Procedure: MINST

Conventional SRP

Active Comparator group

Description:

Conventional non-surgical mechanical treatment using piezoelectric device (PiezoLED, Kavo) and standard Gracey curettes under local anaesthesia.

Treatment:

Procedure: Conventional SRP