Minimally Invasive Treatment of Hypertensive Basal Ganglia Hemorrhage by Transfrontal Keyhole Neuroendoscopy

Peking University

Status: Unknown

Conditions: Basal Ganglia Hemorrhage

Treatments: Procedure: Small bone window craniotomy for hematoma removal under microscope; Procedure: Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal

Study type: Observational

Funder types: Other

Identifiers

NCT04958525

M2020543

Details and patient eligibility

About

To compare the prognosis of patients with hypertensive intracerebral hemorrhage treated by two different surgical methods, and to clarify the therapeutic effect of minimally invasive surgery, so as to find a better surgical method that can reduce surgical trauma and mortality and improve the prognosis of patients

Full description

In this study, a cohort observation method was adopted to observe a total of 52 patients who underwent two surgical procedures, namely, removal of hematoma in basal ganglo-region by keyhole neuroendoscopy under frontal ultrasound guidance and removal of hematoma by craniotomy microsurgery. They were divided into the endoscopic surgery group and the microsurgery group. In the endoscopic surgery group, 26 patients underwent removal of hematoma in basal ganglo-region by keyhole neuroendoscopy under frontal ultrasound guidance.In the microsurgery group, 26 cases were treated with craniotomy microsurgery for hematoma removal. The clearance rate of surgical hematoma, surgical safety, GCS score, GOS score, nerve fiber injury and postoperative complications were observed in the two groups 1 week, 1 month and 3 months after surgery.To observe and analyze whether endoscopic surgery group has advantages in improving hematoma clearance rate and efficacy

Enrollment: 52 estimated patients

Sex: All

Ages: 30 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CT scan was used to diagnose cerebral hemorrhage in basal ganglia region. The amount of bleeding was 30-50ml, and no cerebral hernia was formed.
• Age between 30 and 70
• The onset is longer than 24 hours and less than 72 hours.
• Informed consent of the patient and/or their relative.

Exclusion criteria

• Brain injury, hemorrhage caused by intracranial aneurysm or cerebral arteriovenous malformation.
• Coagulation dysfunction
• Insufficiency of vital organs of heart, liver, kidney or lung
• Previous history of stroke with functional loss
• Intracranial or systemic infection
• Poor blood pressure control

Trial design

52 participants in 2 patient groups

Endoscopic Surgery Group

Description:

After a full evaluation of the patient's condition, the informed consent was signed to perform keyhole neuroendoscopic ultrasound-guided hematoma removal for the patient.

Treatment:

Procedure: Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal

Microsurgery group

Description:

After a full evaluation of the patient's condition, the informed consent was signed to perform small bone window craniotomy for hematoma removal under microscope for the patient.

Treatment:

Procedure: Small bone window craniotomy for hematoma removal under microscope