Minimizing Fall-Related Injury in Older Adults: a Motor Learning Approach

University of Kansas

Status: Completed

Conditions: Fall Injury; Mobility Limitation; Fall Patients

Treatments: Other: Otago Exercise Program; Other: FAST Program

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05260034

R21AG073892 (U.S. NIH Grant/Contract)

STUDY00147362

Details and patient eligibility

About

Falls are the leading cause of accidental injury and injury-related death among older adults. Despite evidence that falls can be prevented, fall related injuries have not declined over time. Current fall injury prevention techniques targeting mobility and bone strength have merit yet their effectiveness is limited. Indeed, a recent Patient Centered Outcomes Research Institute/National Institute on Aging funded pragmatic trial of individualized multifactorial strategy to prevent serious fall injuries in over 5500 seniors revealed no difference in fall injuries between the intervention and standard care arm. The inconclusive results of the investigation may be due in part to focusing on fall prevention rather than mitigation of fall-related impact acceleration and forces - the "fundamental variables" for injury prevention. A fall-related injury occurs when the body hits the ground with force that is greater than tissue strength. Development of innovative approaches that focus on fundamental variables of injury prevention is needed.

Full description

Impact forces and body accelerations can be mitigated by performing specific movement patterns during the impact phase of a fall. The investigators, along with others have postulated and provided preliminary evidence that older adults can learn specific movement patterns (enacted during the impact phase of a fall), such as the tuck and roll that significantly reduce impact forces and minimize the risk of injury. The investigators' recent Randomized Clinical Trial (RCT) that examined the FAlling Safely Training (FAST) program in 17 older adults with low fall risk found that following 2 hours of training, the FAST group reduced their hip impact force by 33% and head acceleration by 59% and demonstrated retention. The procedures were feasible and safe in relatively healthy older adults with low fall risk. Despite the promise of this approach, perhaps the most important issue for real world translation is whether at-fall risk older adults with known balance impairment, a key target group who would most benefit from this training, can safely learn to fall with reduced impact forces and thus potentially fewer injuries using this paradigm. The immediate goal of this investigation is to determine the safety and feasibility of FAST training in an at-fall risk older adult group, the key measurable stages of FAST mastery, and, most importantly, the effect size, compared to modified Otago Exercise Program (an evidence-based fall risk reduction program) controls, to inform a larger future trial. To maximize safety, participants will utilize a protective helmet, and hip protector while landing on a cushioned pad. In addition, using a motor learning approach, the investigators will determine and measure key stages of the technique that can be mastered and measured as intermediate measures to document training progression.

Enrollment: 33 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Have balance impairment as indicated by <10s on unipedal stance
• History of fall injury in the last year; or, two more falls in the last year; or, afraid of falling because of problems with balance or walking
• Have no history of tumbling, gymnastic or martial art experience or currently engagement of 150+ minutes/week of vigorour aerobic activity
• No clinical osteoporosis
• DEXA (dual energy X-ray absorptiometry) determined bone mineral density of the hip of t is greater than or equal to -2.3

Exclusion criteria

• Outside of age range
• Unable to speak or comprehend written/spoken English
• Cognitive impairment as indicated by Saint Louis University Memory Scale (<25)
• Unable to ambulate household distances
• Intact standing balance as indicated by >10s of unipedal stance
• Currently receiving physical therapy
• Presence of clinical osteoporosis
• Uncorrected vision or hearing or vestibular dysfunction
• Major neurological conditions, such as stroke, Parkinson's Disease, vertigo that affect the ability to ambulate or perform daily tasks
• Currently taking medications, including, coumadin, dual oral anticoagulants (apixaban, rivaroxaban), lovenox
• Conditions may lead to (internal) bleeding, such as thrombocytopenia, hemorrhagic diathesis

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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33 participants in 2 patient groups

Otago Group

Active Comparator group

Description:

The control group will receive balance exercises adapted from the evidenced-based Otago Exercise program. Briefly, all eight sessions (\~30 min) will involve balance exercises and strength exercises using ankle weights, and will progressively increase as performance improves by increasing resistance or the difficulty of the balance exercises (e.g., reducing base of support).

Treatment:

Other: Otago Exercise Program

FAST Group

Experimental group

Description:

Participants randomized to the intervention arm will undergo the FAST program, a progressive safe-falling training based on the tuck and roll strategy. As part of the FAST program, participants will train 30 minutes twice a week for a period of four weeks under the supervision of a trained researcher. Participants will wear protective gear (knee, hip, head) and they will complete a 10-minute stretching exercise routine to minimize the risk of injury.

Treatment:

Other: FAST Program