Minimizing Ventricular Pacing

Military Institute od Medicine National Research Institute

Status: Unknown

Conditions: First Degree Atrioventricular Block.; Sinus Node Disease.

Treatments: Device: Standard atrioventricular (AV) delay.; Device: Prolonging atrioventricular (AV) delay.

Study type: Interventional

Funder types: Other

Identifiers

NCT01611389

83562

N N402 533539 (Other Grant/Funding Number)

Details and patient eligibility

About

The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality of life and other heart failure measures.

Enrollment: 60 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• prolonged PQ interval > 200 ms,
• percentage of right ventricular pacing with standard AV delay > 90.

Exclusion criteria

• second or third degree atrioventricular block,
• permanent atrial fibrillation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Long AV delay.

Experimental group

Treatment:

Device: Prolonging atrioventricular (AV) delay.

Short AV delay.

Active Comparator group

Treatment:

Device: Standard atrioventricular (AV) delay.