Minirin Versus Oxybutynin for Nocturnal Enuresis in Children

Hormozgan University of Medical Sciences

Status and phase: Completed; Phase 3

Conditions: Nocturnal Enuresis

Treatments: Drug: Minirin; Drug: Oxybutynin

Study type: Interventional

Funder types: Other

Identifiers

NCT02538302

92.121.505

Details and patient eligibility

About

Nocturnal enuresis is among the most common disorders in children. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.

Full description

Nocturnal enuresis is among the most common disorders in children. Several pharmacological and non-pharmacological treatments are available for nocturnal enuresis. Studies for reaching the best pharmacological treatment for this disorder are continuing. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.

Enrollment: 66 patients

Sex: All

Ages: 5 to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >5 years old
• Nocturnal enuresis
• Candidate for pharmacological treatment

Exclusion criteria

• Children who their parents did noted filled the informed consent form
• Impossibility of follow up during the study period
• History of seizure
• History of rheumatologic disorders such as sjogren's disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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66 participants in 2 patient groups

Minirin

Experimental group

Description:

120 microgram per day for 2 months, then 60 microgram per day for 2 months, then 60 microgram every two days for two months

Treatment:

Drug: Minirin

Oxybutynin

Active Comparator group

Description:

5 mg Oxybutynin twice a daily for 6 months

Treatment:

Drug: Oxybutynin