miRNA Profile in Aneurysmal Subarachnoid Haemorrhage

The Chinese University of Hong Kong

Status: Completed

Conditions: Subarachnoid Hemorrhage

Study type: Observational

Funder types: Other

Identifiers

NCT03344744

miSAH003

Details and patient eligibility

About

The investigators aim to investigate and understand the circulating miRNA profiles after acute aneurysmal subarachnoid haemorrhage and underlying pathological significance.

Full description

1. The investigators aim to investigate the miRNA classifier for delayed cerebral infarction after aneurysmal subarachnoid haemorrhage;
2. The investigators aim to investigate the corresponding circulating and CSF miRNA profiles.

Enrollment: 100 patients

Sex: All

Ages: 21 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Aneurysmal subarachnoid hemorrhage patients within the first 72 hours or Healthy volunteers

Exclusion criteria

Previous neurological diseases such as stroke or dementia

Trial design

100 participants in 3 patient groups

SAH with DCI

Description:

Aneurysmal subarachnoid haemorrhage patients with delayed cerebral infarction

SAH nonDCI

Description:

Aneurysmal subarachnoid haemorrhage patients without delayed cerebral infarction

Control

Description:

Healthy volunteers