ClinicalTrials.Veeva

Menu

Mirror Therapy Rehabilitation for Motor Functional Neurological Disorders. (FND-mirror)

Civil Hospices of Lyon logo

Civil Hospices of Lyon

Status

Completed

Conditions

Functional Neurological Symptom Disorder

Treatments

Other: One-on-one rehabilitation program including computerized mirror therapy in addition to standard rehabilitation.

Study type

Interventional

Funder types

Other

Identifiers

NCT04739176
69HCL20_1094

Details and patient eligibility

About

Motor functional neurological disorders (FND) correspond to motor symptoms that are unexplained by an organic lesion but are due to cerebral dysfunction. Patients with these disorders have high rates of disability and health care utilization, and their quality of life is as impaired as that of patients with an "organic" disease. Accompanying these patients in their often-complex health journey represents a socio-economic and human challenge that demands interdisciplinary collaboration. Rehabilitation is seen as an important part of the therapy for motor FND. However, further research is needed to refine appropriate interventions and to create evidence-based recommendations. In this study, patients suffering from a functional neurological motor disorder of the upper limb will be included in a novel rehabilitation protocol that includes computerized mirror therapy. The study will used a multiple baseline, across subjects, single-case experimental design (SCED). In this type of design, each subject is his own control, with individual parameters being repeatedly measured in the presence and absence of the intervention of interest (computerized mirror therapy). Computerized mirror therapy could restore the coherence between the motor program and its execution. The investigators hypothesize that this process could re-normalize upper-limb motor activity and that this will have a beneficial impact on manual dexterity, quality of life, and mental representation capacities of the upper limb.

The objective of this project is to use the single case experimental design method to investigate the efficacy of rehabilitation with computerized mirror therapy for patients suffering from motor neurological disorders (FND) of the upper limb.

Enrollment

5 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age ≥ 18 years old,
  • Included in the PULSES program (University Program of Liaison and Care for Somatoform Etiologies),
  • Announcement and explanation of the diagnosis already given to the patient,
  • Motivated to participate in the project,
  • Diagnosed with any type of motor functional neurological disorder : partial or complete deficits and abnormal movements,
  • With a lateralized disorder (limited to one hemi-body) involving at least the upper limb,
  • Disorder must primarily involve the distal part of the upper-limb (fingers, wrist),
  • Admitted to the day hospital at Henry Gabrielle Hospital during the study,
  • Given free, informed consent in writing after being informed orally and in writing of how the study will proceed.

Exclusion criteria

  • Patients with visual disorders such as uncorrected diplopia, blindness or low visual acuity (corrected or uncorrected),
  • Pregnant, parturient and breastfeeding women,
  • Patients under a legal protection measure such as guardianship or curatorship
  • Patients not affiliated to a social security scheme (French Social Security) or beneficiaries of a similar scheme.

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

5 participants in 1 patient group

One-on-one rehabilitation program
Experimental group
Treatment:
Other: One-on-one rehabilitation program including computerized mirror therapy in addition to standard rehabilitation.

Trial contacts and locations

1

Loading...

Central trial contact

Jacques LUAUTE, MD, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems