Misoprostol Before and After Cesarean Section

sarah mohamed hassan

Status and phase: Unknown; Phase 3

Conditions: Post Partum Hemorrhage

Treatments: Drug: rectal misoprostol 600mg

Study type: Interventional

Funder types: Other

Identifiers

NCT03463070

1122345

Details and patient eligibility

About

comparison of the effect of misoprostol before and after cesarean on the blood loss

Full description

70 women who received 600 mg misoprostol rectally preoperatively versus 70 women who received 600 mg misoprostol postoperatively at operating theatre

Enrollment: 140 estimated patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women not in active labor have reactive non-stress test.
• No contraindications to prostaglandins.
• Have no history of coagulopathy.

Exclusion criteria

• Placenta previa.
• Maternal hypertension.
• Diabetes mellitus.
• Previous CS and those with active labor.
• Multiple Fibroid uterus.
• Multiple pregnancies or polyhydramnios.
• Previous myomectomy, previous history of PPH.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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140 participants in 2 patient groups

preoperative misoprostol group

Active Comparator group

Description:

70 women who received 600 mg misoprostol rectally preoperatively before cesarean section

Treatment:

Drug: rectal misoprostol 600mg

postoperative misoprostol group

Active Comparator group

Description:

70 women who received 600 mg misoprostol postoperatively at operating theatre after cesarean section

Treatment:

Drug: rectal misoprostol 600mg