Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort

University of California Irvine (UCI)

Status: Completed

Conditions: Type 2 Diabetes Mellitus; Metabolic Syndrome

Treatments: Device: Diffuse Optical Spectroscopy

Study type: Observational

Funder types: Other

Identifiers

NCT00786721

20022608.

Details and patient eligibility

About

There has been increasing support for our hypothesis that mitochondrial dysfunction plays an important role in the etiology of Type 2 Diabetes Mellitus and the overlapping Metabolic Syndrome.

Full description

Once the mitochondrial defect(s) of these subjects has been defined, the data will be used to develop two non-invasive screening tools to detect mitochondrial defects in Diabetes Mellitus and Metabolic Syndrome patients.

The device call Diffuse Optical Spectroscopy develope at Beckman Laser Instituteis is non-invasive measurement technique, to measure the properties of the muscle tisuue and vascular activity (calf, bicep, or the brain)to evaluate the patient's metabolic status and and to assess muscle mitochondrial OXPHOS function.

Enrollment: 9 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chinese descent and have been clinically diagnosed with diabetes mellitus (DM) or have met the study criteria for metabolic syndrome (MS).

Exclusion criteria

• non chiness descent

Trial design

9 participants in 1 patient group

Diffuse Optical Spectroscopy

Description:

muscle properties scanning

Treatment:

Device: Diffuse Optical Spectroscopy