Mitra v Fingerprick Tacrolimus Creatinine

NHS Trust

Status: Unknown

Conditions: Transplant;Failure,Kidney

Treatments: Diagnostic Test: Mitra

Study type: Interventional

Funder types: Other

Identifiers

NCT03601208

18RE007

Details and patient eligibility

About

Patients with kidney transplant have blood tests very often. This is normally done in hospital and using a needle inserted into the vein. Two tests are important for kidney transplant patients - creatinine to monitor the health of the kidney; and tacrolimus to measure the level of the medicine which prevents rejection. The investigators would like to compare a fingerprick microsampling method to the standard venous blood. The fingerprick test is the same done by patients with diabetes and we use a microsampling tip which looks like a cotton bud to draw up a small amount of blood. Each tip draws up exactly 10 microlitres which is two drops. The investigators want to compare the results of creatinine and tacrolimus done through the two methods. In the future, this would allow patients to do their creatinine and tacrolimus test at home. The tips dry completely and can be posted to a laboratory. We hope this will make life easier for transplant patients and also help them engage more with the care of their condition.

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Kidney transplant recipients. Taking tacrolimus

Exclusion criteria

Unable to consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Blood sample

Experimental group

Description:

Venepuncture vs fingerprick test using Mitra volumetric absorptive microsampling (VAMs)

Treatment:

Diagnostic Test: Mitra