MItral Regurgitation Risk Assessment and CLinical modElling (MIRACLE)

Sun Yat-sen University

Status: Enrolling

Conditions: Mitral Regurgitation (MR); Mitral Insufficiency

Study type: Observational

Funder types: Other

Identifiers

NCT06876883

MIRACLE study

Details and patient eligibility

About

Mitral regurgitation (MR) is a common valvular heart disease worldwide, and untreated severe MR is associated with an elevated risk of heart failure and mortality. According to causes, MR could be divided into primary or secondary MR. The risk factors of mortality or heart failure hospitalization in different types of MR patients are under intensive investigation.

MItral Regurgitation risk Assessment and CLinical modElling (MIRACLE) study is a prospective cohort study including adult patients diagnosed with ≥ moderate MR during hospitalization. Comprehensive echocardiographic examination was conducted at baseline evaluating valvular heart disease severity, atrial and ventricular systolic/diastolic function, pulmonary artery systolic pressure (PASP), etc. We aim to evaluate the prognostic risk factors of patients with MR and construct a prognostic clinical model to guide clinical decision-making.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with ≥ moderate mitral regurgitation during hospitalization.
• Aged over 18 yrs.

Exclusion criteria

• Patients unable to provide written consent.

Trial design

2,000 participants in 1 patient group

Patients with MR

Description:

Patients with ≥ moderate mitral regurgitation