MiTy Kids (Metformin in Women With Type 2 Diabetes in Pregnancy Kids Trial)
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Conditions
Details and patient eligibility
About
The prevalence of diabetes in pregnancy is rising in all maternal age groups. There is increasing evidence that in-utero exposure to maternal diabetes is associated with an increased risk of obesity and type 2 diabetes in children and adults. There is an urgent need to reduce these increasing rates of obesity and diabetes in subsequent generations.
The MiTy Trial (Metformin in Women with Type 2 Diabetes in Pregnancy Trial) is a CIHR-funded multi-centre, randomized controlled trial of women with type 2 diabetes in pregnancy (sample size n=500). The MiTy Trial is looking to determine the effect of the addition of metformin to a standard regimen of insulin in women with diabetes, on perinatal morbidity and mortality.
The MiTy Kids Trial is a follow-up to the MiTy Trial which will determine whether treatment with metformin during pregnancy in women with type 2 diabetes will lead to a reduction in adiposity and improvement in insulin resistance in the offspring of women with diabetes at 2 years of age.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Offspring of women with type 2 diabetes who participated (or are participating) in the MiTy trial.
Exclusion criteria
- Offspring with major congenital anomalies.
Trial design
287 participants in 2 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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