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MK-6194 Site of Injection Study in Healthy Adult Participants (MK-6194-013)

Merck Sharp & Dohme (MSD) logo

Merck Sharp & Dohme (MSD)

Status and phase

Completed
Phase 1

Conditions

Healthy

Treatments

Biological: MK-6194

Study type

Interventional

Funder types

Industry

Identifiers

NCT06649877
6194-013
MK-6194-013 (Other Identifier)

Details and patient eligibility

About

The goal of this study is to learn what happens to MK-6194 in a healthy person's body when different injection sites are used. Researchers will compare what happens to MK-6194 in a healthy person's body when it is injected into the abdomen and when it is injected into the thigh. Researchers think that the average amount of MK-6194 in a person's body over time will be similar when injected into the thigh or abdomen. They also want to learn if it is safe to inject MK-6194 into the abdomen and thigh, and if people tolerate it.

Enrollment

16 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

The key inclusion criteria include but are not limited to the following:

  • Is in good health
  • Has a body mass index (BMI) within 18 to 35 kg/m2 and weighs at least 50 kg

Exclusion criteria

The key exclusion criteria include but are not limited to the following:

  • Has a history of clinically significant endocrine, gastrointestinal (GI), cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
  • Has a history of cancer

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

16 participants in 2 patient groups

Abdomen Injection
Experimental group
Description:
Participants will receive a single dose of MK-6194 injected into the abdomen.
Treatment:
Biological: MK-6194
Thigh Injection
Experimental group
Description:
Participants will receive a single dose of MK-6194 injected into the thigh.
Treatment:
Biological: MK-6194

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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