MK0476 Study in Adult Patients With Acute Asthma (0476-322)

Organon

Status and phase: Completed; Phase 3

Conditions: Asthma

Treatments: Drug: montelukast sodium; Drug: Comparator: Placebo

Study type: Interventional

Funder types: Industry

Identifiers

NCT00229970

0476-322

MK0476-322

2005_084

Details and patient eligibility

About

This study evaluates the efficacy and safety of MK0476 intravenous administration in adult patients with acute asthma.

Enrollment: 225 patients

Sex: All

Ages: 15 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult Patients With Acute Asthma Attacks

Exclusion criteria

• Patient Has Any Known Or Suspected, Acute Or Chronic Cause For Their Pulmonary Symptoms Other Than Asthma (E.G., Copd, Chronic Heart Failure, Etc.)
• Patient Has A Smoking History (20 Cigarettes Per Day) Of More Than 15 Years
• Patient Has A Disease Of The Cardiovascular, Hepatic, Renal, Hematologic Systems, Or Other Severe Disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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225 participants in 3 patient groups

1

Experimental group

Description:

Placebo

Treatment:

Drug: Comparator: Placebo

2

Experimental group

Description:

MK0476 7 mg injection

Treatment:

Drug: montelukast sodium

3

Experimental group

Description:

MK0476 14 mg injection

Treatment:

Drug: montelukast sodium