MLPR As A Diagnostic Marker For Acute Pulmonary Embolism

Ain Shams University

Status

Completed

Conditions

Diagnosis

Pulmonary Embolism (Diagnosis)

Treatments

Diagnostic Test: Monocyte to Large Platelet Ratio (MLPR)

Study type

Observational

Funder types

Other

Identifiers

NCT07023705

FMASU MLPR 286

Details and patient eligibility

About

A retrospective study to assess the utility of hematological marker (monocyte to large platelet ratio) to diagnose patients with pulmonary embolism

Full description

The investigators conducted a retrospective review of emergency department records of patients who presented with signs and symptoms suggestive of pulmonary embolism (PE) and underwent CT pulmonary angiography (CTPA) for diagnosis. Hematological laboratory findings obtained prior to any treatment were collected and compared between two groups based on CTPA results: those with confirmed PE (CT positive) and those without PE (CT negative).

Enrollment

37 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Only patients with the results of full blood count and white blood cell differentiation, measured before the treatment of suspected PE.
Patients underwent CT pulmonary angiography to confirm or exclude pulmonary embolism diagnosis.

Exclusion criteria

Patient with history of any myeloproliferative disorder, myelofibrosis, Glanzmann thrombasthenia, May-Hegglin anomaly, Bernard-Soulier syndrome, suspicion of disseminated intravascular coagulation.
Patient receiving any anticoagulant drug at a therapeutic dose.
Patient with blood transfusion in the last 2 months.
Patients with acute coronary syndrome, pulmonary edema.
Patient on immunosuppressive drugs , Oral contraceptive pills .
Patients with severe renal or hepatic disease.
Patients with Stroke.
Patients with malignancy.