Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

Sage Bionetworks

Status: Unknown

Conditions: Basal Ganglia Diseases; Parkinsonian Disorders; Neurodegenerative Diseases; Central Nervous System Diseases; Movement Disorders; Parkinson Disease; Brain Diseases

Treatments: Behavioral: Participant open-response writing; Behavioral: Dexterity; Behavioral: Phonation; Other: Parkinson mPower mobile application; Behavioral: Memory; Behavioral: Gait and balance; Behavioral: Participant self-assessment surveys

Study type: Interventional

Funder types: Other

Identifiers

NCT02696603

20141369 (Other Identifier)

201410711

Details and patient eligibility

About

The purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors.

Full description

Living with Parkinson disease means coping with symptoms that change every day. Yet these changes are not tracked frequently enough. Most people with Parkinson disease see a clinician only once or twice a year. This study measures changes in Parkinson disease symptoms in real time using an app. The app remotely monitors Parkinson disease symptoms using surveys and the sensors on mobile devices. This study may contribute to increasing our understanding of the variability in Parkinson disease symptoms. This knowledge could be used to improve quality of life for people living with Parkinson disease.

Enrollment: 20,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age 18 years
2. Have a personal (i.e., not shared) iPhone (4s or newer running iOS 8.0 or later)
3. Be able to read and understand an official language of the country of participation
4. Be able to provide informed consent (i.e., pass assessment quiz)
5. Be willing to follow study procedures

Exclusion criteria

1. Age 17 years or younger
2. Not a resident of the of a country where the app is approved for use
3. Not have a personal (i.e., not shared) iPhone (4s or newer running iOS 8.0 or later)
4. Not be able to read and understand an official language of the country of participation
5. Not be able to give informed consent
6. Not be willing to follow study procedures

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20,000 participants in 2 patient groups

Participants with Parkinson disease

Experimental group

Description:

People who report a diagnosis of Parkinson disease. Participants are invited via the Parkinson mPower mobile application to complete the following behavioral interventions: Participant self-assessment surveys, Phonation, Gait and balance, Memory, Dexterity, and Participant open-response writing.

Treatment:

Behavioral: Participant open-response writing

Behavioral: Memory

Behavioral: Participant self-assessment surveys

Behavioral: Dexterity

Behavioral: Gait and balance

Behavioral: Phonation

Other: Parkinson mPower mobile application

Participants without Parkinson disease

Experimental group

Description:

People who do not report a diagnosis of Parkinson disease. Participants are invited via the Parkinson mPower mobile application to complete the following behavioral interventions: Participant self-assessment surveys, Phonation, Gait and balance, Memory, Dexterity, and Participant open-response writing.

Treatment:

Behavioral: Participant open-response writing

Behavioral: Memory

Behavioral: Participant self-assessment surveys

Behavioral: Dexterity

Behavioral: Gait and balance

Behavioral: Phonation

Other: Parkinson mPower mobile application