Mobilization With Movement (MWM) on Knee Osteoarthritis (OA)

The Hong Kong Polytechnic University

Status: Active, not recruiting

Conditions: Knee Osteoarthritis

Treatments: Other: Movement with Mobilization (MWM); Other: Sham Movement with Mobilization (Sham MWM)

Study type: Interventional

Funder types: Other

Identifiers

NCT05767788

MWMKOA

Details and patient eligibility

About

Movement with mobilization (MWM) is an effective manual therapy to improve pain and function of patients with knee osteoarthritis (OA).

However, immediate, and prolonged effects after prolonged MWM period was under-investigated.

In this double-blinded randomized control trial, 40 patients are needed. The subjects and assessors will be blinded. Subjects in intervention group will receive MWM twice a week and corresponding home exercise for 6 weeks.

Participants in control group will only receive sham treatment with light touch.

The effects on knee pain in visual analogue scale (VAS); flexion and extension range of motion (ROM) by goniometer; strength by hand-held dynamometer; function by Timed Up and Go Test (TUG) and 30-second Chair Stand Test; and health-related quality of life (HRQoL) by Knee Injury and Osteoarthritis Outcome Score (KOOS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) just after, 1-month and 3-month after treatment will be compared with baseline. Six-month after treatment, KOOS and WOMAC will be conducted.

Enrollment: 40 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• History of knee OA for at least 1-year
• Pain intensity level ≥ 3 on a 10-cm Visual Analogue Scale (VAS)
• Both unilateral or bilateral knee pain
• Having morning stiffness less than 30 minutes
• Having crepitus on active movement
• Having bony tenderness
• Having bony enlargement

Exclusion criteria

• Having active inflammatory or infectious knee conditions
• Having bone integrity conditions like osteoporosis
• Having knee joint instability
• Having skin integrity conditions like frail skin or lower limb peripheral vascular disease
• History of hip or knee fracture
• History of knee surgical history
• Use of knee corticosteroid or opioid injection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Movement with Mobilization (MWM)

Experimental group

Description:

Active movement with passive mobilization gliding force

Treatment:

Other: Movement with Mobilization (MWM)

Sham Movement with Mobilization (Sham MWM)

Sham Comparator group

Description:

Active movement with passive light touch gliding force

Treatment:

Other: Sham Movement with Mobilization (Sham MWM)