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Modification of the Local Abnormal Ventricular Activity Only (LAVAONLY)

U

University of Kiel

Status

Completed

Conditions

Ventricular Tachycardia

Treatments

Procedure: Cardiac ablation therapy

Study type

Observational

Funder types

Other

Identifiers

NCT05331716
2021-1232

Details and patient eligibility

About

Local abnormal ventricular activity (LAVA) is composed of high-frequency, mainly low voltage signals that represent near-field signals from slow-conducting tissue and thus potential VT isthmuses. The identification of LAVA potentials and their modification have usually been a complimentary component of the substrate-based modification of scar related ventricular arrhtyhmias. With better identification through technical solutions and improved algorithms, LAVA modification may be feasible for treatment in therapy refractory VT.

Full description

As of 2019 we started LAVA modification only in a subset of patients with therapy refractory ventricular tachycardia. The cohort icludes 55% patient with ischemic cardiomyopathy and 45% with dilated cardiomyopathy. 80% are ICD recipients. These patients were now retrospectively analysed in depth. The endpoint is time to relapse of ventricular tachycardia or ICD shock or death due to malignant arrhythmia. We evaluated all patients we treated accordingly from March 2019 through October 2020. No patient was excluded.

Enrollment

22 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

therapy refractory ventricular arrhythmia

Exclusion criteria

none

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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