Corkscrew Technique: A Novel Modification in Transurethral Resection of Large Prostate (60-100 g) Optimizing Resection Efficacy and Safety: A Double-blind Randomized Controlled Trial

Menoufia University

Status: Completed

Conditions: Prostate; TURP(Transurethral Resection of Prostate); BPH (Benign Prostatic Hyperplasia)

Treatments: Procedure: Corkscrew technique; Procedure: Nesbit technique

Study type: Interventional

Funder types: Other

Identifiers

NCT06901115

Corkscrew technique

Details and patient eligibility

About

Transurethral resection of the prostate (TURP) is still the gold standard for surgical management of enlarged prostate. However, many techniques and minimally invasive procedures are now in the comparative track with Bipolar resection as Laser enucleation.

Multiple drawbacks of Classic TURP problems related to large prostate management as the retreatment after Bipolar resection, another issue that prolonged operative time, Loss of orientation during resection due to rotation of one of the 2 kissing lobe, Bleeding of the 1st lobe resection side make the 2nd lobe resection harder and lengthier, Median lobe resection or bladder neck resection is done at last to avoid sub-trigonal injury. however, due to median lobe obstruction, irrigation is poor during all the resection. length of learning curve, the modification of early median lobe resection carry the risk of sub-trigonal injury.

So, this study is a trial to analyze the effect of new technique in resection of large prostate with good orientation and less time of operation.

Enrollment: 90 patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• BPH causing LUTS with prostate volume between 60 and 100 ml (either by TRUS or CT).
• PSA level below 4 ng/ml.
• IPSS score of 10 and above.

Exclusion criteria

• previous history of prostatic biopsy.
• previous history of acute urinary retention.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups

Nesbit technique group

Sham Comparator group

Description:

patients of this group undergo the classical Nesbit technique.

Treatment:

Procedure: Nesbit technique

Corkscrew technique

Active Comparator group

Description:

patients of this group undergo the novel modified technique.

Treatment:

Procedure: Corkscrew technique