Modified Reporting of Positive Urine Cultures Collected From Long Term Care

Memorial University of Newfoundland

Status: Completed

Conditions: Asymptomatic Bacteriuria; Urinary Tract Infections

Treatments: Behavioral: Modified Report

Study type: Interventional

Funder types: Other

Identifiers

NCT03554603

MUN-04

Details and patient eligibility

About

Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the laboratory for culture results. The restricted report may reduce the rate of inappropriate treatment of AB.

Full description

Positive urine cultures during the study period will be randomized to restricted microbiology laboratory reporting or standard microbiology laboratory reporting. Physician or patient consent will not be collected. Patient records will be assessed by the investigator to determine if patients have AB or urinary tract infection. Physician antibiotic treatment decision in both groups will be collected.

Enrollment: 100 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Consecutive positive urine cultures collected from patients admitted to Long term care facilities will be included. All methods of urine collection will be included (midstream, in-and-out catheterization, indwelling catheter).

Exclusion criteria

1. Positive urine cultures not collected from Long term care facility patients
2. Pregnancy
3. Antibiotic treatment at the time of collection
4. Patients known to have blood neutrophils <1.0 within 7 days of urine collection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Modified Reporting

Experimental group

Description:

Microbiology laboratory will report "Positive urine cultures may represent asymptomatic bacteriuria or urinary tract infection. If urinary tract infection is suspected clinically, please call 777-xxxx (researcher mobile phone) for identification and susceptibility results"

Treatment:

Behavioral: Modified Report

Standard Reporting

No Intervention group

Description:

Microbiology laboratory will report identification and susceptibility results